Almotriptan is a headache medicine that narrows blood vessels around the brain. Almotriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Almotriptan is used to treat migraine headaches in adults and in adolescents who are at least 12 years old. Almotriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Almotriptan should not be used to treat a common tension headache, a headache that causes loss of movement on one side of your body, or any headache that seems to be different from your usual migraine headaches.

Common side effects may include:

• dry mouth;

• nausea, vomiting;

• numbness, tingling, or burning sensation;

• dizziness, drowsiness; or

• mild headache (not a migraine).

Almotriptan dosing information

Usual Adult Dose for Migraine:

Initial dose: 6.25 mg or 12.5 mg orally as a single dose
Repeat dose: If headache is relieved, but returns, may repeat with 1 dose orally provided there is a minimum interval of 2 hours between doses.
Maximum daily dose: 25 mg

Comments:
-The safety of treating an average of more than 4 migraines per month has not been established.
-The 12.5 mg dose tends to be more effective in adults, however as individuals may vary in their response, the dose should be individualized.
-The effectiveness of a second dose has not been established in clinical trials.

Use: For the acute treatment of migraine attacks in patients with a history of migraine with or without aura.

Usual Pediatric Dose for Migraine:

Adolescents (12 to 17 years):
Initial dose: 6.25 mg or 12.5 mg orally as a single dose
Repeat dose: If headache is relieved, but returns, may repeat 1 dose orally provided there is a minimum interval of 2 hours between doses.
Maximum daily dose: 25 mg

Comments:
-The safety of treating an average of more than 4 migraines per month has not been established.
-Individuals may vary in their response, the dose should be individualized.
-The efficacy in adolescents on migraine-associated symptoms (nausea, photophobia, and phonophobia) and the effectiveness of a second dose have not been established in clinical trials.

Use: For the acute treatment of migraine headache pain in patients with a history of migraine attacks with or without aura usually lasting 4 hours or more when untreated.