Synonyms: IL-15; IL15; Interleukin 15

Catalog NO.: FY-EM4721

Reactivity:Mouse

Assay range:15.6–1,000pg/mL

Sensitivity:＜ 5.9pg/mL

Alias:IL-15; IL15; Interleukin 15

Detection Method:Sandwich ELISA, Double Antibody

Size:48T, 96T

Storage:2–8 ℃ for 6 months

CV %（）:Intra-Assay: CV<8%; Inter-Assay: CV<10%

Note: For Research Use Only

IL-15(Interleukin-15) Basic information

Interleukin-15 (IL-15) is a cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces the prolifeMouseion of natural killer cells, i.e. cells of the innate immune system whose principal role is to kill virally infected cells.

Mouse IL-15(Interleukin-15) ELISA Kit test method

Feiyue’s Mouse IL-15(Interleukin-15) Elisa kit is an ELISA reagent for detection of IL-15(Interleukin-15) in Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.This kit uses sandwich ELISA to detect the concentMouseion of IL-15(Interleukin-15) . IL-15(Interleukin-15) -specific monoclonal antibody has been pre-coated in the wells of the supplied microplate. Standards samples and controls are added to interact with the immobilized antibody. A sandwich complex is formed by additional anti- IL-15(Interleukin-15) antibody with HRP-Streptavidin. TMB solution is added to react with the sandwich for ming optical signal measured by microplate reader. The concentMouseion of IL-15(Interleukin-15) in the sample can be calculated by comparing the absorbance of the sample with the standard curve.

Reference:

1. GRCh38: Ensembl release 89: ENSG00000164136 — Ensembl, May 2017

2. GRCm38: Ensembl release 89: ENSMUSG00000031712 — Ensembl, May 2017

3. “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

4. “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

5. Steel JC, Waldmann TA, Morris JC (January 2012). “Interleukin-15 biology and its therapeutic implications in cancer”. Trends in Pharmacological Sciences. 33 (1): 35–41. doi:10.1016/j.tips.2011.09.004. PMC 3327885. PMID 22032984.