Super-resolution microscope visualizing cellular structures and molecular activity at resolutions never before achieved by conventional light microscopy.

Nikon’s N-SIM microscopy system can produce twice the resolution of conventional optical microscopes. Using an innovative approach based on Structured Illumination Microscopy technology licensed from UCSF, the N-SIM enables detailed visualization of minute intracellular structures and their functions.

Twice the Resolution of Conventional Optical Microscopes

N-SIM doubles the resolution of conventional optical microscopes (~115nm in 3D SIM mode*) by combining “Structured Illumination Microscopy” technology licensed from UCSF with Nikon’s renowned CFI Apo TIRF 100x oil objective lens (N.A. 1.49).

Dedicated Super-resolution Objectives

The SR (super-resolution) objectives have been designed for new applications that break the diffraction barrier.

The most recent optical designs using wavefront aberration measurement have been applied to yield superb optical performances with the lowest asymmetric aberration.

Live Cell Super-Resolution Imaging

The combination of fast image capture and the availability of stage top incubation allows live cell imaging at twice the resolution of conventional microscopes.

for more information please visit:

https://www.nikoninstruments.com/Products/Super-resolution/N-SIM-Super-Resolution